Are you looking for a ‘good’ Twitter client for Gnome? Not happy with Twitux? Try Pino. It’s a new Twitter client for Gnome-based desktop environments. It’s a very lightweight app with minimal dependencies. The latest version supports Identi.ca updates and multi-accounts, among many other features. You can shorten longer URLs on the fly with goo.gl and is.gd. The latest version is an experimental version.

If you are using Ubuntu, use the following command-lines to install Pino,

sudo add-apt-repository ppa:vala-team/ppa
sudo add-apt-repository ppa:troorl/pino 
sudo apt-get update
apt-get install pino

More installation instructions can be found at the download center.